H2O2 sensing is required in numerous organic and industrial functions, for which electrochemical sensing is a promising alternative amongst numerous sensing applied sciences. Electrodes and electrocatalysts strongly affect the efficiency of electrochemical H2O2 sensors. Important efforts have been dedicated to electrode nanostructural designs and nanomaterial-based electrocatalysts. Right here, we evaluate the design methods of electrodes and electrocatalysts utilized in electrochemical H2O2 sensors. We first summarize electrodes in numerous constructions, together with rotation disc electrodes, freestanding electrodes, all-in-one electrodes, and consultant business H2O2 probes. Subsequent, we focus on design methods utilized in latest research to extend the variety of energetic websites and intrinsic actions of electrocatalysts for H2O2 redox reactions, together with nanoscale pore structuring, conductive helps, lowering catalyst measurement, alloying, doping, and tunning crystal aspects. Final, we offer our views on future analysis instructions in creating nanoscale constructions and nanomaterials to allow superior electrochemical H2O2 sensors in sensible functions.